Week 4 NFL Betting Trend: Keep Targeting Winless Teams ATS?

Since 2010, winless Week 4 teams are 31-17-1 (64.6%) against the spread vs. a team with at least one win. The road split is even better.

Cam Skattebo #44 of the New York Giants runs after the catch during the first quarter of the game against the Kansas City Chiefs on September 21, 2025 at MetLife Stadium in East Rutherford, New Jersey.

(Photo by Rich Graessle/Icon Sportswire)

By Week 4, we usually have a solid read on where teams are headed, especially those that start 0–3. The question is whether the market is pricing those winless teams too low. To find out, we examine how winless teams perform against the spread in Week 4 when they face opponents with at least one win. Here’s what we found:

Week 4 Winless Teams Against the Spread (Since 2010)

We looked at every Week 4 matchup since 2010 where a winless team faced an opponent with at least one victory. The goal was simple: track how those winless teams performed against the spread.

Results since 2010:

  • Overall ATS: 31–17–1 (64.6%)
  • Home ATS: 9–8–0 (52.9%)
  • Road ATS: 21–8–1 (72.4%)

There’s a strong trend here: winless teams in Week 4 have covered at a healthy rate, and teams on the road have been especially strong.

The Full List Since 2010

Since 2010, we have found 49 instances in which a winless team has faced a team with at least one win in Week 4. We then pulled up the closing line (per BetIQ custom trends tool) and filtered the data to this list:

DateTeamOpponentWeekLocationSpreadOver/UnderMoneylineScoreMarginAts W/L
2024-09-29CincinnatiCarolina4Away-4.546.5-22534-2410Win
2024-09-29JacksonvilleHouston4Away5.044.520520-24-4Win
2024-09-30TennesseeMiami4Away2.538.013631-1219Win
2023-10-01HoustonPittsburgh4Home3.041.513030-624Win
2023-10-01Las VegasLA Chargers4Away6.549.023517-24-7Loss
2021-09-30JacksonvilleCincinnati4Away7.546.528221-24-3Win
2021-10-03DetroitChicago4Away3.041.513014-24-10Loss
2021-10-03IndianapolisMiami4Away2.542.012527-1710Win
2021-10-03NY GiantsNew Orleans4Away7.542.528027-216Win
2021-10-03NY JetsTennessee4Home5.544.520527-243Win
2020-10-04CincinnatiJacksonville4Home-1.049.5-12033-258Win
2020-10-04NY GiantsLA Rams4Away13.549.06419-17-8Win
2020-10-04PhiladelphiaSan Francisco4Away8.045.528625-205Win
2020-10-05AtlantaGreen Bay4Away5.056.519716-30-14Loss
2019-09-29MiamiLA Chargers4Home14.543.557010-30-20Loss
2019-09-29WashingtonNY Giants4Away3.048.01503-24-21Loss
2019-09-29ArizonaSeattle4Home5.549.020810-27-17Loss
2019-09-29DenverJacksonville4Home-2.537.0-13724-26-2Loss
2018-09-30HoustonIndianapolis4Away-1.048.5-11337-343Win
2018-09-30OaklandCleveland4Home-2.544.5-14045-423Win
2018-09-30ArizonaSeattle4Home3.540.016917-20-3Win
2017-10-01San FranciscoArizona4Away6.543.022515-18-3Win
2017-10-01LA ChargersPhiladelphia4Home-2.048.0-12624-26-2Loss
2017-10-01NY GiantsTampa Bay4Away2.546.012523-25-2Win
2016-10-02JacksonvilleIndianapolis4Neutral1.048.0-11030-273Win
2016-10-02ChicagoDetroit4Home3.548.016017-143Win
2016-10-02ClevelandWashington4Away7.048.028020-31-11Loss
2016-10-02New OrleansSan Diego4Away3.554.016535-341Win
2015-10-01BaltimorePittsburgh4Away-3.044.0-15023-203Push
2015-10-04ChicagoOakland4Home3.044.515022-202Win
2015-10-04New OrleansDallas4Home-3.049.0-15026-206Win
2015-10-05DetroitSeattle4Away10.043.040010-13-3Win
2014-09-28OaklandMiami4Neutral4.041.017014-38-24Loss
2014-09-28Tampa BayPittsburgh4Away7.044.528527-243Win
2014-09-28JacksonvilleSan Diego4Away12.545.049814-33-19Loss
2013-09-29NY GiantsKansas City4Away3.543.51607-31-24Loss
2013-09-29Tampa BayArizona4Home-2.540.0-13410-13-3Loss
2013-09-29JacksonvilleIndianapolis4Home9.542.53303-37-34Loss
2013-09-29WashingtonOakland4Away-3.545.5-18524-1410Win
2012-09-27ClevelandBaltimore4Away11.043.546516-23-7Win
2012-09-30New OrleansGreen Bay4Away7.554.029027-28-1Win
2011-10-02St LouisWashington4Home3.044.013010-17-7Loss
2011-10-02MiamiSan Diego4Away6.545.026016-26-10Loss
2011-10-03IndianapolisTampa Bay4Away10.040.041517-24-7Win
2010-10-03San FranciscoAtlanta4Away7.042.525014-16-2Win
2010-10-03BuffaloNY Jets4Home5.536.521014-38-24Loss
2010-10-03ClevelandCincinnati4Home2.536.511523-203Win
2010-10-03DetroitGreen Bay4Away14.546.080026-28-2Win
2010-10-03CarolinaNew Orleans4Away12.543.555014-16-2Win

Which Teams Qualify for This Trend in 2025?

As we noted last week, backing a winless team against the spread is rarely comfortable. Most of these teams are 0–3 for a reason, and Week 4 makes the call even tougher as injuries accumulate, pricing tightens, and opponents have at least one convincing result on the board.

  • Saints +15.5 at Bills

  • New York Giants +6.5 vs. LA Chargers

The Saints meet the road ATS split that is 72.4%.

Why This Might Be Happening

Two forces likely drive the edge.

  1. Market perception. Records get overweighted by both bettors and models that incorporate prior outcomes. A winless record after three games can inflate spreads in ways that are not fully justified by true strength.
  2. Urgency and planning. Similar to what we noted with the Week 3 trend, teams that start poorly often lean into sharper game plans, higher leverage decisions, and tighter rotations. The difference between 0–3 and 0–4 is massive, and that urgency can translate to performance relative to expectation.

How To Use This Trend

Trends are a starting point, not a blind system. Do not auto-bet every winless team.

  • Price check. If the line moved heavily against the winless side, ask whether injuries or a matchup change actually justify that move.
  • Respect the road data. The road split has been excellent. That does not mean all road spots are buys, but it is a hint that the market sometimes overshoots when a winless team goes on the road.
  • Confirm with fundamentals. Quarterback pressure rates, finishing drives, special teams, and coaching edges still decide outcomes. Let the trend nudge your short list, then make a football case.

Notes on Methodology

  • Sample includes Week 4 only, winless teams versus opponents with at least one win.
  • Pushes are reported explicitly. Win percentages listed above exclude pushes unless noted.
  • Lines reflect closing spreads gathered via the BetIQ Custom Trends Tool.

Bottom Line

For more than a decade, the market has leaned too far against winless teams in Week 4. That does not make every winless side a value play, but it should raise your antenna when the price looks inflated.

Start with the trend, pressure test it with matchup and injury context, and let the numbers guide you to the best of these spots.